Celiac Disease (Sprue)

Celiac condition is also called sprue or non-tropical sprue, affects the small intestine absorption of nutrition. This condition is due to inflammation in the walls of the small intestine. The main cause of this condition is an allergen found in food mainly gluten.

There are two indirect causes of celiac disease:

  • 1- Lack of digestive enzyme at the stomach level that leads to improperly release undigested food particles short of being digested completely. Naturally, undigested particles of undigested food will not be absorbed into the intestinal villi and will end up forming stool. Some of these food particles get trapped in one of the villi. While these food particles are too large to fit or be absorbed through the villi. However, some of these particles manage to be absorbed in the tiny villi and damage the tubes. The flow of large particles damages the tube. These damaged tubes increase the chance for undigested particles to flow into the portal circulation and settle in the liver leading to its inflammation,
  • 2- Excessive treatment with oral antibiotics that affects the walls of the large intestine. The inflammation on the wall of the cecum spreads through the sphincter into the distal (lower) section of the small intestine. The lining of the intestines contains areas called villi, which help absorb nutrients
  • 3- The above two causes lead to food allergies such as gluten, certain carbohydrate which affect nutritional balance leading to mal-absorption
  • 4- Depending on the severity of antibiotic treatments, the quantity of undigested particles and the level of allergies developed in the body; the disease may erupt at any age. The more frequent use of antibiotic treatments, the quantity of undigested particles and the level of allergies;  the more chronic and systemic the sickness in the tissue is.


The symptoms of celiac disease are three types

  • 1- Depending on the amount of the undigested food particles in the body, increases skin conditions proportionately such as: eczema, weight lose, weight gain, hives and purities ’
  • 2- Depending on the amount of antibiotics used, the symptoms of constipation, gas, bloating, diarrhea, and inability to digest carbohydrates and dairy products will increase proportionately
  • 3- Depending on the amount of allergens in the body there will be an increased level of tiredness, fatigue, nausea, vomiting, depression, anxiety, amenorrhea,
  • 4- Children celiac disease may cause dental problems such as enamel teeth defects and teeth discoloration, digestive problems such as diarrhea and constipation nausea, vomiting, in psychology child hyperactivity, irritations, poor appetite, poor weight gain,

The symptoms may vary from severe symptoms in one person to absolutely no symptoms with other people. The symptoms may change from person to person depending on the amount of allergies, food particles and antibiotics.

Blood work notes
The average person with celiac disease may develop blood tests abnormality such as liver enzyme (Alk Phos., and transaminase), complete blood count (CBC),